The verb resign is used when someone walks away from a job or a position.
Bob will resign from his administrative job.
I need to resign from my position as club chairman.
The verb re-sign is used when someone writes their signature a second time. They sign again.
I need to re-sign that document because water got spilled on it.
We will re-sign our will after making some changes.
Use resign when leaving a job or other position. Use re-sign when writing your signature a second time.
It’s your turn. Decide if you should use resign or re-sign in this sentence. I can no longer do the job, so I will ____. Did you figure it out? Good!